Colloquium on September 1st, 2008

Paul Chaikin
New York University

Toward Self-Replication with Colloids

We want to make a non-"biokleptic" system which can self-replicate. The idea is to design colloids with specific and reversible and irreversible interactions, introduce seed motifs, and cycle the system in such a way that a copy is made. Repeating the cycle would double the number of offspring in each generation leading to exponential growth. We're not there yet! We use colloidal particles with bound DNA Watson-Crick sequences for reversible recognition and bound DNA palindrome sequences for linking. They now "work" - recognize, cycle and can be permanently attached as well. So the talk will be on where we are, how we got there and where we're going.