Max-Planck-Institut für Physik komplexer
Systeme
International Workshop on
Biological Evolution and Statistical
Physics
May 10-14, 2000
Inferring Phylogenetic Processes
beyond the One Tree
Mike Charleston
University of Oxford, Evolutionary Biology Group
michael.charleston@zoo.ox.ac.uk
With the wealth of molecular data becoming available to researchers
it is becoming apparent to all that the pursuit of the phylogeny of a group
of organisms not only represents much less of a challenge than it used
to, but that it does not sufficiently address some of the important phylogenetic
questions which can only be answered with such data. The "one tree"
is of little intrinsic interest, unless we can use it to answer biological
questions. This talk will describe some of the ways which are being developed
and used in the Evolution Research Group at the University of Oxford, these
being (i) a novel method for the detection of recombination in viruses,
(ii) use of new models in Coalescent Theory to make inferences about population
demography of HIV, and (iii) the recovery of coevolutionary patterns among
Caribbean Anolis lizards and the malaria which infects them.
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