Max-Planck-Institut für Physik komplexer Systeme

International Workshop on 
Biological Evolution and Statistical Physics
May 10-14, 2000 

    Inferring Phylogenetic Processes beyond the One Tree
    Mike Charleston
University of Oxford, Evolutionary Biology Group
michael.charleston@zoo.ox.ac.uk
With the wealth of molecular data becoming available to researchers it is becoming apparent to all that the pursuit of the phylogeny of a group of organisms not only represents much less of a challenge than it used to, but that it does not sufficiently address some of the important phylogenetic questions which can only be answered with such data.  The "one tree" is of little intrinsic interest, unless we can use it to answer biological questions. This talk will describe some of the ways which are being developed and used in the Evolution Research Group at the University of Oxford, these being (i) a novel method for the detection of recombination in viruses, (ii) use of new models in Coalescent Theory to make inferences about population demography of HIV, and (iii) the recovery of coevolutionary patterns among Caribbean Anolis lizards and the malaria which infects them.
       
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